BRUTRAX- (ANASTROZOLE)- 1mg Tablets- TAJ PHARMA
Anastrozole 1 mg for treatment of Breast Cancer
Anastrozole 1 mg for treatment of Breast Cancer
Anastrozole is used to treat certain
types of breast cancer in women who have already stopped menstruating
(postmenopausal). It is also used for women who have already had other cancer
treatments (e.g., tamoxifen).
Many
breast cancer tumors grow in response to estrogen. This medicine interferes
with the production of estrogen in the body. As a result, the amount of
estrogen that the tumor is exposed to is reduced, limiting the growth of the
tumor.
This
medicine is available only with your doctor's prescription.
Once a
medicine has been approved for marketing for a certain use, experience may show
that it is also useful for other medical problems. Although these uses are not
included in product labeling, anastrozole is used in certain patients with the
following medical conditions:
- Breast cancer, neoadjuvant treatment for hormone receptor-positive, operable or potentially operable, locally advanced disease in postmenopausal women (treatment for advanced breast cancer that may respond to surgery in women who have already stopped menstruating).
This
product is available in the following dosage forms:
- Tablet
For
this medicine, the following should be considered:
Allergies
Tell
your doctor if you have ever had any unusual or allergic reaction to this
medicine or any other medicines. Also tell your health care professional if you
have any other types of allergies, such as to foods, dyes, preservatives, or
animals. For non-prescription products, read the label or package ingredients
carefully.
Pediatric
Appropriate
studies performed to date have not demonstrated pediatric-specific problems
that would limit the usefulness of anastrozole in children.
Geriatric
Appropriate
studies performed to date have not demonstrated geriatric-specific problems
that would limit the usefulness of anastrozole in the elderly.
Pregnancy
Breast
Feeding
There
are no adequate studies in women for determining infant risk when using this
medication during breastfeeding. Weigh the potential benefits against the
potential risks before taking this medication while breastfeeding.
Drug Interactions
Although
certain medicines should not be used together at all, in other cases two
different medicines may be used together even if an interaction might occur. In
these cases, your doctor may want to change the dose, or other precautions may
be necessary. When you are taking this medicine, it is especially important
that your healthcare professional know if you are taking any of the medicines
listed below. The following interactions have been selected on the basis of
their potential significance and are not necessarily all-inclusive.
Using
this medicine with any of the following medicines may cause an increased risk
of certain side effects, but using both drugs may be the best treatment for
you. If both medicines are prescribed together, your doctor may change the dose
or how often you use one or both of the medicines.
- Tamoxifen
Other
Interactions
Certain
medicines should not be used at or around the time of eating food or eating
certain types of food since interactions may occur. Using alcohol or tobacco
with certain medicines may also cause interactions to occur. Discuss with your
healthcare professional the use of your medicine with food, alcohol, or
tobacco.
Other
Medical Problems
The
presence of other medical problems may affect the use of this medicine. Make
sure you tell your doctor if you have any other medical problems, especially:
- Bone problems (osteoporosis) or
- Hypercholesterolemia (high cholesterol or fat in the blood) or
- Ischemic heart disease (heart attack, angina), history of, or
- Liver disease—Use with caution. May make these conditions worse.
- Premenopausal women (have menstrual cycles)— should not be used in these patients.
DOSAGE
The
dose of this medicine will be different for different patients. Follow your
doctor's orders or the directions on the label. The following information
includes only the average doses of this medicine. If your dose is different, do
not change it unless your doctor tells you to do so.
The
amount of medicine that you take depends on the strength of the medicine. Also,
the number of doses you take each day, the time allowed between doses, and the
length of time you take the medicine depend on the medical problem for which
you are using the medicine.
- For oral dosage form (tablets):
- For breast cancer:
- Adults—1 milligram (mg) once a day.
- Children—Use and dose must be determined by your doctor.
STORAGE
OF MEDICINE
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
- Keep out of the reach of children.
- Do not keep outdated medicine or medicine no longer needed.
PRECAUTIONS
It is
important that your doctor check your progress at regular visits to make sure
that this medicine is working properly. Blood tests may be needed to check for
unwanted effects.
It is
unlikely that a postmenopausal woman may become pregnant. But, you should know
that using this medicine while you are pregnant could harm your unborn baby.
Use an effective form of birth control to keep from getting pregnant. If you
think you have become pregnant while using the medicine, tell your doctor right
away.
This
medicine may cause a serious type of allergic reaction called anaphylaxis.
Anaphylaxis can be life-threatening and requires immediate medical attention.
Call your doctor right away if you have itching; hives; hoarseness; trouble
breathing; trouble swallowing; or any swelling of your hands, face, or mouth
while you are using this medicine.
This
medicine may decrease bone mineral density when used for a long time. A low
bone mineral density can cause weak bones or osteoporosis. If you have any
questions about this, talk to your doctor.
This
medicine may increase your cholesterol or fat in the blood. If this happens,
your doctor may give you medicine to lower the cholesterol and fat.
Stop
taking this medicine and check with your doctor right away if you start having
chest pains or shortness of breath. This medicine may increase the chance of
heart attack or stroke in women who have a history of ischemic heart disease.
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